Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954957 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL30129411 | 0.78 | ERN1 (0.46) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL6076848 | 0.78 | ERN1 (0.46) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL29952796 | 0.78 | ERN1 (0.46) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL6626617 | 0.78 | ERN1 (0.46) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL29952839 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL8544546 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL2119952 | 0.75 | ERN1 (0.39) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL4640515 | 0.75 | ERN1 (0.43) | ALDH1A1MAPTKDM4EMEN1MPI | |
| SCHEMBL2214871 | 0.75 | ERN1 (0.39) | ALDH1A1MAPTKDM4EMEN1MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816900-B | Synthesis method of 2-chloro-5-methylpyridine-3-formaldehyde | 宁夏瑞泰科技股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-113816900-A | Synthetic method of 2-chloro-5-methylpyridine-3-formaldehyde | 宁夏瑞泰科技股份有限公司 | 2021-12-21 | — | — | CN | claimed |
| EP-1348699-B1 | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde | COUNCIL SCIENT IND RES (IN) | 2010-05-05 | — | — | EP | claimed |
| US-7666883-B2 | 2-[(2-Chloro-5-methyl pyridine-3-yl)(hydroxy)methyl]acrylonitrile; against chloroquine sensitive and chloroquine resistant Plasmodium falciparum; treating malarial; chemical preparation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-02-23 | — | — | US | claimed |
| EP-1924558-B1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2010-01-13 | — | — | EP | claimed |
| EP-1346984-B1 | Process for the preparation of 2-chloro-5-methylpyridine-3- carbaldehyde | COUNCIL SCIENT IND RES (IN) | 2008-08-06 | — | — | EP | claimed |
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | claimed |
| US-20070117822-A1 | Novel antimalarial baylis-hillman adducts and a process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-05-24 | — | — | US | claimed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | claimed |
| US-6737529-B2 | REACTING N-BENZYL-N-(1-PROPENYL)ACETAMIDE WITH VILSEMIER REAGENT, HEATING, THEN EXTRACTING WTIH METHYLENE CHLORIDE AND SEPARATION SOLVENT; USEFUL AS INTERMEDIATE IN PREPARATION OF PHARMACEUTICALS AND PESTICIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-05-18 | — | — | US | claimed |
| EP-1348699-A1 | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde | Council of Scientific and Industrial Research (IN) | 2003-10-01 | — | — | EP | claimed |
| EP-1346984-A1 | Process for the preparation of 2-chloro-5-methylpyridine-3- carbaldehyde | Council of Scientific and Industrial Research (IN) | 2003-09-24 | — | — | EP | claimed |
| US-20030176705-A1 | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-09-18 | — | — | US | claimed |
| US-6566528-B1 | Reacting 2-chloro-3-chloromethyl-5-methyl pyridine and 2-nitroimino-1,3-diazacyclopentane in the presence of a base and an organic solvent; insecticides that act at the nicotinic acetylcholine receptor | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-20 | — | — | US | claimed |
| EP-1306374-A1 | 1-(2-chloro-5-methyl-3-pyridylmethyl)-2-nitroiminoimadozolidine and a process for the preparation thereof | Council of Scientific and Industrial Research (IN) | 2003-05-02 | — | — | EP | claimed |
| US-20030083350-A1 | 1-(2-CHLORO-5-METHYL-3-PYRIDYLMETHYL)-2-NITROIMINIOMIDAZOLIDINE AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | US | claimed |
| US-6479664-B1 | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-11-12 | — | — | US | claimed |
| EP-0702003-A2 | Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes | BAYER AG (DE) | 1996-03-20 | — | — | EP | claimed |
| CN-113816900-B | Synthesis method of 2-chloro-5-methylpyridine-3-formaldehyde | 宁夏瑞泰科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-0702003-A2 | Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117822-A1 | Novel antimalarial baylis-hillman adducts and a process for the preparation thereof | HBS1L, SSBP1, QARS1 | ALDH1A1 1459/4885MAPT 3203/4885KDM4E 524/4885 |
| US-20030176705-A1 | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde | CYP3A5, DDT, CHRM5 | ALDH1A1 625/4885MAPT 2752/4885KDM4E 134/4885 |
| US-20030083350-A1 | 1-(2-CHLORO-5-METHYL-3-PYRIDYLMETHYL)-2-NITROIMINIOMIDAZOLIDINE AND PROCESS FOR THE PREPARATION THEREOF | CYP1B1, CYP2C9, CYP1A1 | ALDH1A1 229/4885MAPT 4610/4885KDM4E 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.