Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645520 | 0.82 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| Hydrochloric Acid SCHEMBL28853901 | 0.80 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL30302109 | 0.80 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL5162856 | 0.78 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL4423573 | 0.78 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| Oxalic Acid SCHEMBL30696169 | 0.78 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL30688000 | 0.76 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL30687999 | 0.76 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL428389 | 0.75 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2GAAPOLB | |
| SCHEMBL29524553 | 0.75 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279848-A | Pan-JAKs inhibitor and application thereof | 四川海思科制药有限公司 | 2021-01-29 | — | — | CN | disclosed |