Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511146 | 1.00 | RORC (0.46) | RORC | |
| SCHEMBL28537942 | 0.88 | RORC (0.39) | RORC | |
| SCHEMBL28518833 | 0.80 | RORC (0.44) | RORC | |
| SCHEMBL28511837 | 0.80 | RORC (0.44) | RORC | |
| SCHEMBL28515118 | 0.78 | RORC (0.48) | RORC | |
| SCHEMBL28510284 | 0.76 | RORC (0.48) | RORC | |
| SCHEMBL28510283 | 0.76 | RORC (0.48) | RORC | |
| SCHEMBL23189614 | 0.72 | RORC (0.40) | RORC | |
| SCHEMBL23189613 | 0.72 | RORC (0.40) | RORC | |
| SCHEMBL23189638 | 0.72 | RORC (0.40) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566901-A | Phenyl-substituted pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112292373-A | Pyridylpyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112292183-A | 6-aminopyridin-3-yl-pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |