SCHEMBL28512267

SCHEMBL28512267

CCOC(COc1ccc(C(=O)O)c(O)c1)Oc1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
HPGD P15428 5/20 0.43
CYP3A4 P08684 4/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 2/20 0.43
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
XDH P47989 1/20 0.42
SLC22A12 Q96S37 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 2/20 0.41
PGR P06401 2/20 0.41
SLC6A2 P23975 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28512270 0.96 NPC1 (0.44) NPC1RAB9AHPGDCYP3A4ALDH1A1
SCHEMBL10694407 0.92 MAOB (0.46) HPGDALDH1A1MAPK1XDHSLC22A12
SCHEMBL23640375 0.78 MAOB (0.56) HPGDCYP3A4ALDH1A1MAPK1HTT
SCHEMBL27097925 0.78 ALDH1A1 (0.53) HPGDCYP3A4ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL29773892 0.78 ALDH1A1 (0.53) HPGDCYP3A4ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL29378251 0.76 PPARD (0.56) NPC1RAB9AHPGDCYP3A4ALDH1A1
SCHEMBL51025 0.76 PPARD (0.56) NPC1RAB9AHPGDCYP3A4ALDH1A1
SCHEMBL477573 0.76 NPC1 (0.56) NPC1RAB9AHPGDCYP3A4ALDH1A1
SCHEMBL539138 0.76 ALDH1A1 (0.55) HPGDALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL8605634 0.75 NPC1 (0.54) NPC1RAB9AHPGDCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334319-A Thermosensitive recording material 王子控股株式会社 2021-02-05 CN disclosed