Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029488 | 1.00 | HTT (0.40) | HTTBTKALDH1A1ATRATRIP | |
| SCHEMBL82980 | 0.80 | NPC1 (0.46) | HTTALDH1A1LMNALRRK2KMT2A | |
| SCHEMBL82981 | 0.80 | NPC1 (0.46) | HTTALDH1A1LMNALRRK2KMT2A | |
| SCHEMBL30068291 | 0.77 | PDE1B (0.40) | HTTALDH1A1ATRATRIPLMNA | |
| SCHEMBL26646946 | 0.77 | PDE1B (0.40) | HTTALDH1A1ATRATRIPLMNA | |
| SCHEMBL19719450 | 0.77 | HTT (0.52) | HTTALDH1A1LMNAMEN1TSHR | |
| SCHEMBL12798197 | 0.72 | LMNA (0.41) | HTTALDH1A1LMNALRRK2KMT2A | |
| SCHEMBL22944343 | 0.72 | BTK (0.35) | BTK | |
| SCHEMBL30547494 | 0.68 | KDM4E (0.51) | HTTALDH1A1LMNAMEN1TSHR | |
| SCHEMBL25559759 | 0.68 | KDM4E (0.51) | HTTALDH1A1LMNAMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300133-A | Heterocyclic compound and application thereof | 深圳微芯生物科技股份有限公司 | 2021-02-02 | — | — | CN | disclosed |