Flurothyl

Flurothyl

SCHEMBL28512508

FC(F)(F)COCC(F)(F)F.[NaH]

nearest known ligand 0.36

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
HTT P42858 1/20 0.35
ALDH1A1 P00352 4/20 0.33
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
THRB P10828 1/20 0.31
G6PD P11413 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flurothyl SCHEMBL120937 0.96 CA1 (0.38) CA1CA2CA9HTTALDH1A1
SCHEMBL31189779 0.85 CA1 (0.33) CA1CA2CA9HTTALDH1A1
Flurothyl SCHEMBL1717869 0.82 HTT (0.36) CA1CA2CA9HTTALDH1A1
SCHEMBL1591167 0.80 CA1 (0.35) CA1CA2CA9HTTALDH1A1
SCHEMBL12544850 0.80 CA1 (0.35) CA1CA2CA9HTTALDH1A1
SCHEMBL19664195 0.79 CA1 (0.31) CA1CA2CA9
SCHEMBL7154378 0.79 CA1 (0.31) CA1CA2CA9
SCHEMBL10202617 0.79 CYP2C19 (0.33) CA1CA2CA9
Flurothyl SCHEMBL22529162 0.79 CA1 (0.31) CA1CA2CA9ALDH1A1
SCHEMBL1999207 0.79 ALDH1A1 (0.33) CA1CA2CA9ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112299960-B Synthesis method and application of bis (2,2, 2-trifluoroethyl) ether 江苏蓝色星球环保科技股份有限公司 2022-03-29 CN disclosed
CN-112299960-A Synthesis method and application of bis (2,2, 2-trifluoroethyl) ether 江苏蓝色星球环保科技股份有限公司 2021-02-02 CN disclosed