Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 13/20 | 0.45 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505850 | 0.82 | HCRTR1 (0.32) | — | |
| SCHEMBL29242138 | 0.77 | XPO1 (0.47) | XPO1ADRB2 | |
| SCHEMBL27627602 | 0.75 | XPO1 (0.42) | XPO1HTTADRB2 | |
| SCHEMBL28770223 | 0.74 | XPO1 (0.40) | XPO1 | |
| SCHEMBL28503221 | 0.72 | XPO1 (0.40) | XPO1HTT | |
| SCHEMBL855354 | 0.70 | XPO1 (0.46) | XPO1 | |
| SCHEMBL855385 | 0.70 | XPO1 (0.43) | XPO1HTT | |
| SCHEMBL29027712 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL18150637 | 0.70 | NOTUM (0.44) | XPO1ADRB2 | |
| SCHEMBL18611252 | 0.70 | XPO1 (0.46) | XPO1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105419-B | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112105419-A | Fused ring compound | 豪夫迈·罗氏有限公司 | 2020-12-18 | — | — | CN | disclosed |