SCHEMBL28512889

SCHEMBL28512889

c1ccc(-c2ccccc2Nc2cccc(-n3ccnc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.53
PDGFRB P09619 1/20 0.53
BCR P11274 1/20 0.53
SRC P12931 1/20 0.53
PDGFRA P16234 1/20 0.53
PRKCA P17252 1/20 0.53
PRKCD Q05655 1/20 0.53
CYP3A4 P08684 2/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
IDO1 P14902 1/20 0.47
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
MAPT P10636 1/20 0.44
CYP19A1 P11511 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
PDE3B Q13370 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31440677 1.00 ABL1 (0.53) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL21362368 0.83 CYP3A4 (0.62) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL7128731 0.81 ABL1 (0.53) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL7130668 0.80 ABL1 (0.53) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL8592858 0.76 ABL1 (0.67) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL7119129 0.76 KDR (0.59) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL4865755 0.76 MEN1 (0.71) CYP3A4MEN1KMT2AALOX15TSHR
SCHEMBL25354337 0.75 MEN1 (0.54) SRCPRKCAPRKCDCYP3A4MEN1
SCHEMBL7117380 0.75 ALOX5 (0.58) ABL1PDGFRBBCRSRCPDGFRA
SCHEMBL28226596 0.74 ALK (0.49) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300124-A Organic electroluminescent device and organic metal complex used for organic electroluminescent device 三星显示有限公司 2021-02-02 CN disclosed