SCHEMBL28513162

SCHEMBL28513162

CC(OCc1ccccc1)C(=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP9 P14780 2/20 0.43
MMP8 P22894 2/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1706675 0.85 KMT2A (0.56) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL138280 0.85 KMT2A (0.56) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL27757196 0.85 KMT2A (0.56) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL138281 0.85 KMT2A (0.56) SLC1A3SLC1A2SLC1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL8687912 0.83 KMT2A (0.54) SLC1A3SLC1A2SLC1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL8687505 0.83 KMT2A (0.54) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL357741 0.83 ALDH1A1 (0.55) SLC1A3SLC1A2SLC1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL7686303 0.83 KMT2A (0.54) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL1911343 0.83 ALDH1A1 (0.55) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL13983833 0.83 ALDH1A1 (0.55) SLC1A3SLC1A2SLC1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174823-B Intermediate for synthesizing 2, 2-dimethyl-3-oxetanone and preparation method and application thereof 南京富润凯德生物医药有限公司 2023-12-01 CN disclosed
CN-112174823-B Intermediate for synthesizing 2, 2-dimethyl-3-oxetanone and preparation method and application thereof 南京富润凯德生物医药有限公司 2023-12-01 CN disclosed
CN-112174823-A Intermediate for synthesizing 2, 2-dimethyl-3-oxetanone and preparation method and application thereof 南京富润凯德生物医药有限公司 2021-01-05 CN disclosed
CN-112174823-A Intermediate for synthesizing 2, 2-dimethyl-3-oxetanone and preparation method and application thereof 南京富润凯德生物医药有限公司 2021-01-05 CN disclosed