Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422179 | 0.97 | TSHR (0.41) | TSHRTDP1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11582372 | 0.93 | TSHR (0.39) | TSHRTDP1ALDH1A1LMNA | |
| Water SCHEMBL11564722 | 0.93 | TSHR (0.39) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL16168029 | 0.84 | TSHR (0.37) | TSHRTDP1 | |
| Bromide SCHEMBL8461150 | 0.73 | TSHR (0.39) | TSHRTDP1ALDH1A1LMNA | |
| Bromide SCHEMBL14890343 | 0.73 | TSHR (0.39) | TSHRTDP1ALDH1A1LMNA | |
| Bromide SCHEMBL28460603 | 0.72 | TSHR (0.31) | TSHR | |
| Bromide SCHEMBL3028711 | 0.71 | SLC22A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL3850922 | 0.71 | TSHR (0.44) | TSHRTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL315435 | 0.70 | DNM1 (0.44) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341983-B | Waterborne polyurethane adhesive and preparation method thereof | 上海都昱新材料科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-112341983-A | Waterborne polyurethane adhesive and preparation method thereof | 上海都昱新材料科技有限公司 | 2021-02-09 | — | — | CN | disclosed |