Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indoline SCHEMBL27276532 | 0.92 | PDPK1 (0.46) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL27754980 | 0.92 | DRD2 (0.46) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL7621649 | 0.89 | DRD2 (0.43) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL6769550 | 0.89 | GFER (0.45) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL4685686 | 0.86 | DRD2 (0.50) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL27516735 | 0.86 | SMN1; SMN2 (0.47) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL4156871 | 0.85 | PDPK1 (0.46) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL5120533 | 0.85 | DRD2 (0.46) | DRD2DRD4PDPK1PARP1PARP10 | |
| Indoline SCHEMBL30159318 | 0.84 | PARP1 (0.40) | DRD2DRD4PDPK1PARP1PARP10 | |
| Benzenesulfonamide SCHEMBL5635260 | 0.84 | CA1 (0.53) | PDPK1PARP1PARP10PARP11CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225684-B | Synthetic method of organic intermediate 5-iodoindole | 山东省农业科学院农产品研究所 | 2022-06-17 | — | — | CN | disclosed |
| CN-112225684-A | Synthetic method of organic intermediate 5-iodoindole | 山东省农业科学院农产品研究所 | 2021-01-15 | — | — | CN | disclosed |