Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 13/20 | 0.41 |
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21515088 | 1.00 | NAALAD2 (0.60) | NAALAD2CTSSCTSKGHSRCTSL | |
| SCHEMBL21494648 | 0.91 | NAALAD2 (0.73) | NAALAD2CTSSCTSKGHSRCTSL | |
| SCHEMBL21494649 | 0.91 | NAALAD2 (0.73) | NAALAD2CTSSCTSKGHSRCTSL | |
| SCHEMBL23030234 | 0.90 | NAALAD2 (0.47) | NAALAD2CTSSCTSK | |
| SCHEMBL28905981 | 0.85 | NAALAD2 (0.64) | NAALAD2CTSSCTSKGHSRCTSL | |
| SCHEMBL27938378 | 0.80 | NAALAD2 (0.48) | NAALAD2CTSSCTSKGHSRCTSL | |
| SCHEMBL7341365 | 0.80 | NAALAD2 (0.50) | NAALAD2GHSR | |
| SCHEMBL21515089 | 0.79 | NAALAD2 (0.60) | NAALAD2GHSR | |
| SCHEMBL28504133 | 0.79 | NAALAD2 (0.60) | NAALAD2GHSR | |
| Hydrochloric Acid SCHEMBL21494731 | 0.78 | NAALAD2 (0.58) | NAALAD2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-A | 2, 6-diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2021-01-12 | — | — | CN | disclosed |