SCHEMBL28513823

SCHEMBL28513823

CC(C)(C)N(C(=O)OS(=O)(=O)c1c(F)cc(F)c(Br)c1F)c1ccsn1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30662740 0.80 SCN8A (0.45) SCN8A
SCHEMBL19627715 0.80 SCN8A (0.45) SCN8A
SCHEMBL19613985 0.75 SCN8A (0.33) SCN8A
SCHEMBL28740402 0.65 LMNA (0.31)
SCHEMBL19627662 0.64 SCN8A (0.60) SCN8A
SCHEMBL29447365 0.64 SCN8A (0.60) SCN8A
SCHEMBL22331230 0.62 SCN8A (0.35) SCN8A
SCHEMBL29447345 0.61 SCN8A (0.33) SCN8A
SCHEMBL28740308 0.61
SCHEMBL20256275 0.59 SCN8A (0.42) SCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262142-B Benzenesulfonamide compounds and their use as therapeutic agents 泽农医药公司 2023-11-14 CN disclosed
CN-112262142-A Benzenesulfonamide compounds and their use as therapeutic agents 泽农医药公司 2021-01-22 CN disclosed