Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | ARNT | P27540 | 2/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437881 | 0.77 | L3MBTL1 (0.62) | MEN1KMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL4589324 | 0.75 | MAPK13 (0.68) | MEN1KMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL2904234 | 0.75 | MERTK (0.68) | MEN1KMT2AALDH1A1LMNAMERTK | |
| SCHEMBL1624206 | 0.73 | MAPT (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11740053 | 0.73 | MAPT (0.55) | MEN1KMT2AALDH1A1LMNAARNT | |
| SCHEMBL11441106 | 0.73 | HSD17B10 (0.66) | MEN1KMT2AALDH1A1ATMARNT | |
| SCHEMBL13206377 | 0.73 | MAPK1 (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4933766 | 0.72 | MAPT (0.67) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2330801 | 0.72 | SMN1; SMN2 (0.61) | MEN1KMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL1625931 | 0.72 | KMT2A (0.46) | MEN1KMT2AMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704579-B | Benzimidazole compound synthesis method based on iron-catalyzed redox coupling reaction | 中国农业大学 | 2021-12-14 | — | — | CN | disclosed |
| CN-111704579-A | Benzimidazole compound synthesis method based on iron-catalyzed redox coupling reaction | 中国农业大学 | 2020-09-25 | — | — | CN | disclosed |