Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015638 | 0.84 | PBRM1 (0.54) | PBRM1MAPK1ALDH1A1AHRRAB9A | |
| SCHEMBL3080778 | 0.80 | PBRM1 (0.41) | PBRM1MAPK1ALDH1A1AHRRAB9A | |
| SCHEMBL9649146 | 0.79 | ALDH1A1 (0.43) | MAPK1ALDH1A1NFKB1SMN1; SMN2MAPT | |
| SCHEMBL22030567 | 0.77 | PBRM1 (0.48) | PBRM1MAPK1ALDH1A1AHRRAB9A | |
| SCHEMBL11400639 | 0.77 | HSP90AA1 (0.49) | MAPK1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22030564 | 0.76 | PBRM1 (0.47) | PBRM1MAPK1ALDH1A1AHRRAB9A | |
| SCHEMBL31626473 | 0.75 | MAPK1 (0.50) | PBRM1MAPK1ALDH1A1AHRRAB9A | |
| SCHEMBL6172768 | 0.74 | CYP1A2 (0.49) | MAPK1ALDH1A1RAB9ANFKB1SMN1; SMN2 | |
| SCHEMBL21304266 | 0.74 | ALDH1A1 (0.48) | MAPK1ALDH1A1RAB9ANFKB1SMN1; SMN2 | |
| SCHEMBL16441477 | 0.74 | MAPK1 (0.60) | PBRM1MAPK1ALDH1A1AHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300088-A | Synthetic method of 2, 4-dihalogen-6-aryl substituted triazine derivative | 郑州海阔光电材料有限公司 | 2021-02-02 | — | — | CN | disclosed |