Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 9/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410640 | 1.00 | LMNA (0.79) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL8193596 | 0.91 | LMNA (0.87) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285379 | 0.91 | LMNA (0.87) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL19376355 | 0.91 | LMNA (0.81) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL6420868 | 0.89 | LMNA (0.94) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL8425098 | 0.89 | LMNA (0.94) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL13394000 | 0.89 | LMNA (0.94) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL8966859 | 0.89 | LMNA (0.94) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL26123316 | 0.89 | LMNA (0.80) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL28441036 | 0.89 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | claimed |
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |