Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649093 | 1.00 | GRM5 (0.41) | GRM5VCPFFAR1SMN1; SMN2S1PR2 | |
| SCHEMBL28509399 | 0.91 | VCP (0.44) | GRM5VCPFFAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28501871 | 0.83 | APP (0.44) | VCPSMN1; SMN2S1PR2ALDH1A1HSP90AA1 | |
| SCHEMBL28499562 | 0.82 | VCP (0.60) | VCPSMN1; SMN2ALDH1A1HSP90AA1MAPT | |
| SCHEMBL28644592 | 0.82 | VCP (0.51) | GRM5VCPFFAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28501872 | 0.82 | VCP (0.51) | GRM5VCPFFAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31614569 | 0.78 | VCP (0.68) | GRM5VCPFFAR1SMN1; SMN2S1PR2 | |
| SCHEMBL5592873 | 0.78 | VCP (0.68) | GRM5VCPFFAR1SMN1; SMN2S1PR2 | |
| SCHEMBL141877 | 0.76 | GRM5 (0.45) | GRM5FFAR1FFAR4 | |
| SCHEMBL141876 | 0.76 | GRM5 (0.45) | GRM5FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062735-B | Synthesis method of isoselenazole derivative | 温州大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112159364-B | Synthetic method of isothiazole derivative | 温州大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-112159364-A | Synthetic method of isothiazole derivative | 温州大学 | 2021-01-01 | — | — | CN | disclosed |
| CN-112062735-A | Synthesis method of isoselenazole derivative | 温州大学 | 2020-12-11 | — | — | CN | disclosed |