SCHEMBL28514751

SCHEMBL28514751

NC(=O)CSn1ncnn1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333082 0.65
SCHEMBL28906737 0.65 POLB (0.37) SMN1; SMN2
SCHEMBL1179541 0.63 L3MBTL1 (0.35) SMN1; SMN2
SCHEMBL1760612 0.58 KMT2A (0.39) SMN1; SMN2
SCHEMBL11675118 0.57 POLB (0.35)
SCHEMBL3069757 0.57
SCHEMBL7381738 0.56
SCHEMBL341630 0.54 CYP2C19 (0.47) SMN1; SMN2
SCHEMBL2798772 0.54
SCHEMBL1642952 0.54 HSD17B10 (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663182-B Glutamine metabolism inhibitor compound 杭州健昵福生物科技有限公司 2020-12-22 CN disclosed