Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514843 | 1.00 | L3MBTL1 (0.47) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL28267278 | 0.78 | L3MBTL1 (0.40) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL28267276 | 0.78 | L3MBTL1 (0.40) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL9011646 | 0.77 | TSHR (0.67) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL9011734 | 0.77 | TSHR (0.67) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL9011624 | 0.77 | TSHR (0.67) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL9011715 | 0.77 | TSHR (0.67) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL25195898 | 0.75 | TSHR (0.64) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL2640223 | 0.75 | TSHR (0.70) | L3MBTL1TDP1TSHRGBA1UGCG | |
| SCHEMBL8608254 | 0.74 | CA1 (0.50) | L3MBTL1TDP1TSHRGBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111333-B | Chiral gem-disilyl alkane compound and synthesis method and application thereof | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |