Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28451525 | 0.97 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Acetic Acid SCHEMBL968509 | 0.97 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Acetic Acid SCHEMBL28461054 | 0.90 | KDM4E (0.38) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Allylamine SCHEMBL27826020 | 0.88 | ALDH1A1 (0.41) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Allylamine SCHEMBL4317227 | 0.88 | ALDH1A1 (0.41) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Allylamine SCHEMBL21268032 | 0.88 | ALDH1A1 (0.41) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Methacrylic Acid SCHEMBL2792667 | 0.88 | KDM4E (0.37) | SMN1; SMN2TSHRMAPTKMT2AKDM4E | |
| Acetic Acid SCHEMBL31425205 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRMAPTFFAR3LCK | |
| Methacrylic Acid SCHEMBL4704719 | 0.85 | KDM4E (0.38) | SMN1; SMN2TSHRMAPTKMT2AKDM4E | |
| Acetic Acid SCHEMBL31288509 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105922778-B | Ink jet recording method and ink jet recording apparatus | 精工爱普生株式会社 | 2021-02-09 | — | — | CN | disclosed |