SCHEMBL28515136

SCHEMBL28515136

O=C1C=CC=C2C(=O)NC=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3883020 0.74
SCHEMBL3885051 0.74
SCHEMBL625895 0.71
SCHEMBL29441814 0.65
SCHEMBL28686392 0.62
SCHEMBL30484451 0.60
SCHEMBL27626616 0.60 MAOA (0.56)
SCHEMBL26686729 0.60
SCHEMBL28042159 0.60
SCHEMBL4419955 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240299366-A1 IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2024-09-12 US disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed
CN-110551126-B Amino acid modified S, R-heptacyclic aldehyde, and synthesis, activity and application thereof 首都医科大学 2021-01-29 CN disclosed
CN-110551128-B Amino acid modified S, R-heptacyclic aldehyde, synthesis, activity and application thereof 首都医科大学 2020-10-16 CN disclosed
CN-110551126-A Amino acid modified S, R-heptacyclic aldehyde, and synthesis, activity and application thereof UNIV CAPITAL MEDICAL SCIENCES 2019-12-10 CN disclosed