SCHEMBL2851519

SCHEMBL2851519

CC1=C(C)C(C)(C)C([Rh])=C1C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL14954087 0.97 CTSD (0.33) CTSD
SCHEMBL14954190 0.97 CTSD (0.33) CTSD
Hydrochloric Acid SCHEMBL810310 0.97 CTSD (0.33) CTSD
Iodide SCHEMBL810380 0.97 CTSD (0.33) CTSD
Bromide SCHEMBL809754 0.97 CTSD (0.33) CTSD
Hydrochloric Acid SCHEMBL23388159 0.97 CTSD (0.33) CTSD
Formaldehyde SCHEMBL16161196 0.92 CTSD (0.41) CTSD
Carbon Monoxide SCHEMBL204677 0.92 CTSD (0.36) CTSD
Formaldehyde SCHEMBL15319409 0.92 CTSD (0.41) CTSD
SCHEMBL10610781 0.89 CTSD (0.34) CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874702-A Isoquinoline quinazoline Process for preparing ketone compounds 河南农业大学 2025-04-25 CN claimed
CN-116836180-B Nitrogen and oxygen hetero-polycyclic aromatic hydrocarbon and synthetic method and application thereof 河南农业大学 2025-03-11 CN claimed
CN-119409635-A Fluoro methyl substituted indeno [1,2-b ] pyridine compound with anticancer activity and synthesis method thereof 河南师范大学 2025-02-11 CN claimed
CN-117720537-B Axial chiral indole-furan catalyst and preparation method and application thereof 江苏师范大学 2024-07-09 CN claimed
CN-113196514-B Method for producing layers using a mixed solvent system 牛津大学科技创新有限公司 2024-07-02 CN claimed
CN-118063449-A Method for synthesizing isoindolinone from olefin and iodophor 南方医科大学 2024-05-24 CN claimed
CN-117720537-A Axial chiral indole-furan catalyst and preparation method and application thereof 江苏师范大学 2024-03-19 CN claimed
CN-117567415-A Process for preparing 4-fluoro-3-phenylnaphtho [2,1-b ] furan-2-one derivatives 盐城工学院 2024-02-20 CN claimed
CN-117531542-A Supported Salen ligand coordinated metal Rh catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-02-09 CN claimed
CN-114907246-B Total synthesis method of vitamin A, derivative thereof and deuterated compound thereof 复旦大学 2024-02-06 CN claimed
CN-110627730-A Novel method for efficiently synthesizing 4-alkenyl quinazoline by C-H activation/cyclization reaction catalyzed by transition metal 四川大学 2019-12-31 CN claimed
CN-110183423-A A kind of new method activating synthesis 3- aryl Isatine derivatives by C-H using isatin diazonium as Cabbeen donor 四川大学 2019-08-30 CN claimed
EP-1534704-B1 PROCESS FOR PREPARING 5-(4-FLUOROPHENYL)-1-¬2-((2R,4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)ETHYL|-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE WARNER LAMBERT CO (US) 2007-08-01 EP claimed
US-7084282-B2 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide WARNER-LAMBERT COMPANY LLC (US) 2006-08-01 US claimed
US-20060106228-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide NELSON JADE D 2006-05-18 US claimed
EP-1534704-A1 PROCESS FOR PREPARING 5-(4-FLUOROPHENYL)-1-[2-((2R,4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE Warner-Lambert Company LLC (US) 2005-06-01 EP claimed
US-20040220254-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide NELSON JADE D (US) 2004-11-04 US claimed
US-20040068121-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide NELSON JADE D (US) 2004-04-08 US claimed
WO-2004014896-A1 PROCESS FOR PREPARING 5-(4-FLUOROPHENYL)-1-[2-((2R,4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE WARNER-LAMBERT COMPANY LLC (US) 2004-02-19 WO claimed
US-5563290-A Method for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1996-10-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220254-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide HMGCR, ORAI1, RYR2 CTSD 1348/4885
US-20040068121-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide HMGCR, ORAI1, RYR2 CTSD 1251/4885
US-20060106228-A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide HMGCR, ORAI1, RYR2 CTSD 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.