SCHEMBL28515317

SCHEMBL28515317

CCOC(=O)C(C#N)C(C(=O)OCC)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 5/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 4/20 0.36
GAA P10253 3/20 0.36
MEN1 O00255 3/20 0.36
HTT P42858 2/20 0.35
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411806 0.86 SMN1; SMN2 (0.42) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL10535054 0.83 SMN1; SMN2 (0.45) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL7706526 0.82 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL6925032 0.80 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL6925024 0.80 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL13858310 0.80 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL6925027 0.80 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL5524988 0.79 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1ALDH1A1TSHRKMT2A
SCHEMBL9054019 0.79 ALDH1A1 (0.48) L3MBTL1ALDH1A1KMT2AGAAMEN1
SCHEMBL235785 0.79 ALDH1A1 (0.48) L3MBTL1ALDH1A1KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023553-A Catalyst for olefin polymerization reaction, catalyst system and application 中国石油化工股份有限公司 2023-04-28 CN disclosed
CN-112661881-B Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2022-12-13 CN disclosed
CN-112661881-A Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-04-16 CN disclosed
CN-109111535-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-107344979-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109111538-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-107344978-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2020-06-09 CN disclosed