Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449935 | 0.80 | FFAR1 (0.60) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL28509990 | 0.79 | CA12 (0.53) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL28483464 | 0.79 | FFAR1 (0.55) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL29985519 | 0.79 | MAPT (0.63) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL2831073 | 0.78 | TP53 (0.59) | FFAR1CYP2A6ACACBFFAR4TP53 | |
| SCHEMBL5050178 | 0.78 | CYP2A6 (0.64) | FFAR1CYP2A6ACACBTP53 | |
| SCHEMBL8228398 | 0.78 | CYP2A6 (0.64) | FFAR1CYP2A6ACACBTP53 | |
| SCHEMBL28515434 | 0.77 | FFAR1 (0.46) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL28359812 | 0.76 | FFAR1 (0.44) | FFAR1CYP2A6ACACBCHRM2S1PR1 | |
| SCHEMBL8454687 | 0.76 | FFAR1 (0.63) | FFAR1CYP2A6ACACBCHRM2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110656346-B | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-02 | — | — | CN | claimed |