Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496761 | 0.93 | HDAC11 (0.49) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21496677 | 0.89 | KDR (0.48) | HDAC11KDR | |
| SCHEMBL21496701 | 0.83 | HDAC11 (0.50) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25932035 | 0.81 | HDAC11 (0.47) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25932026 | 0.81 | HDAC11 (0.47) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23771284 | 0.78 | HDAC11 (0.45) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30039180 | 0.78 | HDAC11 (0.45) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23771283 | 0.78 | HDAC11 (0.45) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30039897 | 0.78 | HDAC11 (0.45) | HDAC11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28512205 | 0.78 | HDAC11 (0.45) | HDAC11MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292370-A | Isoindolines as HDAC inhibitors | 瓦洛早期发现股份有限公司 | 2021-01-29 | — | — | CN | disclosed |