SCHEMBL28515673

SCHEMBL28515673

CCC(C)Oc1cccc(C#N)c1OC(C)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
XDH P47989 1/20 0.37
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
S1PR1 P21453 2/20 0.34
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
MAOA P21397 1/20 0.33
HTR2B P41595 1/20 0.33
S1PR3 Q99500 1/20 0.33
S1PR5 Q9H228 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28312799 0.84 DYRK1A (0.35) MCHR1SMN1; SMN2MAPK1XDHNPC1
SCHEMBL4433039 0.83 DHODH (0.35) MCHR1
SCHEMBL28311175 0.76 MAPK1 (0.43) MCHR1SMN1; SMN2MAPK1XDHPOLB
SCHEMBL8970180 0.75 MCHR1 (0.45) MCHR1
SCHEMBL2043468 0.75 MCHR1 (0.45) MCHR1TDP1L3MBTL1
SCHEMBL2410915 0.73 MCHR1 (0.48) MCHR1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL28986732 0.73 XDH (0.46) XDHS1PR1MAOAS1PR3S1PR5
SCHEMBL2410917 0.73 MCHR1 (0.48) MCHR1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL9001613 0.73 SMN1; SMN2 (0.40) SMN1; SMN2MAPK1XDHPOLBGAA
SCHEMBL31490284 0.72 MCHR1 (0.51) MCHR1ADRA2AADRA2BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705848-B One-dimensional organic semiconductor nanocoil and preparation method and application thereof 中国科学院化学研究所 2021-02-26 CN disclosed