SCHEMBL28515873

SCHEMBL28515873

NC(=O)OC1(O)CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22660781 0.83
SCHEMBL8487791 0.77 KDM4E (0.36) KDM4EKMT2A
SCHEMBL3398233 0.76 TSHR (0.36)
Hydrochloric Acid SCHEMBL28777414 0.76 KDM4E (0.35) KDM4EKMT2A
SCHEMBL19691434 0.76 KDM4E (0.44) KDM4EKMT2A
SCHEMBL28516465 0.76 KDM4E (0.44) KDM4EKMT2A
Hydrochloric Acid SCHEMBL28376257 0.74 KDM4E (0.42) KDM4EKMT2A
SCHEMBL3844048 0.74 KDM4E (0.38) KDM4EKMT2A
SCHEMBL28609456 0.72 KDM4E (0.41) KDM4EKMT2A
SCHEMBL29749234 0.72 KDM4E (0.37) KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112313235-A Pyrazolo-triazine and/or pyrazolo-pyrimidine derivatives as selective inhibitors of cyclin dependent kinases 奎利恩特有限公司 2021-02-02 CN disclosed