SCHEMBL28516002

SCHEMBL28516002

Fc1cccc(C#Cc2ccccc2Sc2ccccc2C#Cc2cccc(F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.55
CA2 P00918 3/20 0.55
CA9 Q16790 3/20 0.55
GRM5 P41594 14/20 0.45
CA1 P00915 2/20 0.45
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28357654 0.87 CA12 (0.52) CA12CA2CA9GRM5CA1
SCHEMBL28513833 0.80 CYP1A2 (0.38) CA12CA2CA9GRM5
SCHEMBL28509992 0.79 GRM5 (0.49) CA12CA2CA9GRM5CA1
SCHEMBL31286312 0.79 CA12 (0.62) CA12CA2CA9GRM5CA1
SCHEMBL9302636 0.79 CA12 (0.62) CA12CA2CA9GRM5CA1
SCHEMBL28516005 0.77 CA12 (0.56) CA12CA2CA9GRM5CA1
SCHEMBL717450 0.77 CA12 (0.59) CA12CA2CA9GRM5CA1
SCHEMBL28481617 0.73 CA12 (0.52) CA12CA2CA9GRM5CA1
SCHEMBL28788080 0.72 CA12 (0.55) CA12CA2CA9GRM5CA1
SCHEMBL9304700 0.71 CA12 (0.62) CA12CA2CA9GRM5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110656346-B Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device 南京工业大学 2021-02-02 CN claimed