Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | GRM5 | P41594 | 10/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286312 | 1.00 | CA12 (0.62) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL717450 | 0.93 | CA12 (0.59) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL9304700 | 0.91 | CA12 (0.62) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL718613 | 0.87 | CA12 (0.52) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL25490046 | 0.85 | GRM5 (0.50) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL29978832 | 0.85 | GRM5 (0.50) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL15540865 | 0.85 | CA12 (0.50) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL848355 | 0.85 | CA12 (0.50) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL935880 | 0.85 | CA12 (0.50) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL10300114 | 0.85 | CA12 (0.53) | CA12CA2CA9CA1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530327-A | method for synthesizing β -iodoalkenylsulfone compound with participation of iodine | 江西师范大学 | 2018-09-14 | — | — | CN | disclosed |
| WO-2017011920-A1 | COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-01-26 | — | — | WO | disclosed |
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |
| US-5178791-A | Ferroelectricity; electrooptics | DISPLAYTECH, INC. (US) | 1993-01-12 | — | — | US | disclosed |