Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516061 | 1.00 | MEN1 (0.53) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17708682 | 0.89 | MEN1 (0.54) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17708680 | 0.89 | MEN1 (0.54) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL28650606 | 0.88 | MEN1 (0.47) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17709051 | 0.85 | CYP19A1 (0.50) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17709048 | 0.85 | CYP19A1 (0.50) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17709052 | 0.85 | CYP19A1 (0.50) | MEN1KMT2AUSP2MAPTMAOB | |
| SCHEMBL17708757 | 0.84 | CYP19A1 (0.55) | MAOBCYP3A4ARCYP19A1 | |
| SCHEMBL17708754 | 0.84 | CYP19A1 (0.55) | MAOBCYP3A4ARCYP19A1 | |
| SCHEMBL17708758 | 0.84 | CYP19A1 (0.55) | MAOBCYP3A4ARCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405337-B | Substituted chromans and methods of use | 艾伯维公司 | 2021-02-09 | — | — | CN | disclosed |