Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877508 | 0.82 | MAPK1 (0.41) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL23554744 | 0.82 | ALDH1A1 (0.43) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL2954148 | 0.82 | LCK (0.43) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL29549606 | 0.82 | ALDH1A1 (0.43) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL2968391 | 0.81 | MAPT (0.42) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL29878249 | 0.80 | NOTUM (0.42) | MAPTMAPK1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL28574774 | 0.79 | KDM4E (0.41) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL23554745 | 0.79 | MAPK1 (0.39) | MAPTMAPK1HPGDGAACYP1A2 | |
| SCHEMBL17417363 | 0.79 | PTGER4 (0.39) | MAPTMAPK1GAACYP1A2RECQL | |
| SCHEMBL23362438 | 0.78 | MAPT (0.46) | MAPTMAPK1GAACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003161-B | Neurotrophic factor tyrosine kinase receptor inhibitors | 正大天晴药业集团股份有限公司 | 2020-10-09 | — | — | CN | disclosed |