SCHEMBL2851613

SCHEMBL2851613

NOP(=O)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42
ANPEP P15144 2/20 0.42
LAP3 P28838 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2851714 0.95 SRC (0.54) SRCL3MBTL1TDP1KDM4ECYP3A4
SCHEMBL28015965 0.87 SRC (0.47) SRCL3MBTL1TDP1KDM4ECYP3A4
SCHEMBL4018818 0.87 SRC (0.47) SRCL3MBTL1TDP1KDM4ECYP3A4
SCHEMBL3888609 0.86 SRC (0.45) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL18116 0.85 SRC (0.64) SRCL3MBTL1TDP1KDM4ECYP3A4
Triphenyl Phosphate SCHEMBL28557783 0.85 SRC (0.64) SRCL3MBTL1TDP1KDM4ECYP3A4
Triphenyl Phosphate SCHEMBL483692 0.85 SRC (0.64) SRCL3MBTL1TDP1KDM4ECYP3A4
Triphenyl Phosphate SCHEMBL28761613 0.85 SRC (0.64) SRCL3MBTL1TDP1KDM4ECYP3A4
Triphenyl Phosphate SCHEMBL28200611 0.83 SRC (0.56) SRCL3MBTL1TDP1KDM4ECYP3A4
Triphenyl Phosphate SCHEMBL15815456 0.82 SRC (0.61) SRCL3MBTL1TDP1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620274-B Method for preparing lignin-based carbon quantum dots with high quantum yield quickly, simply and conveniently 广东工业大学 2023-03-24 CN claimed
CN-118702096-A Method for recycling battery negative electrode graphite, regenerated graphite material prepared by method and application of regenerated graphite material 广东邦普循环科技有限公司 2024-09-27 CN disclosed
CN-118541372-A Bicyclic triazine derivatives for the treatment of cancer 德国癌症研究中心 2024-08-23 CN disclosed
US-11963960-B2 Compounds for treating or inhibiting recurrence of acute myeloid leukemia FLASH THERAPEUTICS, LLC (US) 2024-04-23 US disclosed
CN-116507337-A ATR inhibitors and uses thereof 上海德琪医药科技有限公司 2023-07-28 CN disclosed
EP-4121430-A1 COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA Flash Therapeuttics, LLC (US) 2023-01-25 EP disclosed
US-11352329-B2 HIV protease inhibitors GILEAD SCIENCES, INC. (US) 2022-06-07 US disclosed
CN-113939300-A STAT degradants and uses thereof 凯麦拉医疗公司 2022-01-14 CN disclosed
US-20210299128-A1 COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA RIKEN (JP) 2021-09-30 US disclosed
WO-2021188417-A1 COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA FLASH THERAPEUTICS, LLC (US) 2021-09-23 WO disclosed
CN-1289745-C Flameproof agent for polyester-based textile product and method of flameproof DAIKYO CHEMICAL (JP) 2006-12-13 CN disclosed
CN-1845907-A Guanidine derivatives ACTELION PHARMACEUTICALS LTD (CH) 2006-10-11 CN disclosed
CN-1761673-A guanidine derivatives and their use as neuropeptide FF receptor antagonists ACTELION PHARMACEUTICALS LTD (CH) 2006-04-19 CN disclosed
CN-1606646-A Flameproof agent for polyester-based textile product and method of flameproof DAIKYO CHEMICAL (JP) 2005-04-13 CN disclosed
US-20040249029-A1 Flameproofing agent for polyester-based textile product and method of flameproofing DAIKYO CHEMICAL CO., LTD. (JP) 2004-12-09 US disclosed
EP-1449955-A1 FLAMEPROOFING AGENT FOR POLYESTER BASED TEXTILE PRODUCT AND METHOD OF FLAMEPROOFING Daikyo Chemical Co., Ltd (JP) 2004-08-25 EP disclosed
CN-1057085-C Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives BAYER AG (DE) 2000-10-04 CN disclosed
CN-1108257-A Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives BAYER AG (DE) 1995-09-13 CN disclosed
CN-1102645-A Phenylglycinamides of heterocyclically substituted phenylacetic acid derivatives BAYER AG (DE) 1995-05-17 CN disclosed
CN-1082030-A Propenoyl-imidazole derivatives BAYER AG (DE) 1994-02-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11963960-B2 Compounds for treating or inhibiting recurrence of acute myeloid leukemia MCL1, FLT3, ABL1 SRC 95/4885L3MBTL1 299/4885TDP1 3548/4885
US-11352329-B2 HIV protease inhibitors PRSS1, SERPINB1, FURIN SRC 2825/4885L3MBTL1 2931/4885TDP1 1859/4885
US-20210299128-A1 COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA MCL1, FLT3, ABL1 SRC 95/4885L3MBTL1 299/4885TDP1 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.