Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 12/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505642 | 0.86 | WNT3A (0.55) | WNT3APORCN | |
| SCHEMBL28513444 | 0.85 | WNT3A (0.52) | WNT3AMAPK1 | |
| SCHEMBL28516174 | 0.83 | WNT3A (0.50) | WNT3AMAPK1 | |
| SCHEMBL28508416 | 0.81 | WNT3A (0.57) | WNT3APORCN | |
| SCHEMBL28503743 | 0.81 | WNT3A (0.46) | WNT3AMAPK1PORCN | |
| SCHEMBL28513443 | 0.79 | WNT3A (0.59) | WNT3APORCN | |
| SCHEMBL28506130 | 0.79 | WNT3A (0.54) | WNT3APORCN | |
| SCHEMBL28503709 | 0.79 | WNT3A (0.47) | WNT3APORCN | |
| SCHEMBL28510748 | 0.79 | WNT3A (0.46) | WNT3APORCN | |
| SCHEMBL28906730 | 0.78 | WNT3A (0.47) | WNT3APORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056754-B | WNT pathway inhibitor with embedded urea structure | 苏州信诺维医药科技有限公司 | 2020-12-04 | — | — | CN | disclosed |