Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.46 |
| ▸ | KDR | P35968 | 10/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522398 | 1.00 | EGFR (0.49) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28908582 | 0.97 | EGFR (0.50) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28522716 | 0.94 | KDR (0.50) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28535568 | 0.92 | EGFR (0.51) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28527871 | 0.89 | EGFR (0.51) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28518408 | 0.89 | EGFR (0.51) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28527727 | 0.87 | ACHE (0.48) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28529605 | 0.86 | EGFR (0.53) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28908558 | 0.85 | EGFR (0.49) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28522414 | 0.85 | EGFR (0.49) | EGFRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808031-B | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-111808031-A | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2020-10-23 | — | — | CN | disclosed |