Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTR2B | P41595 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504234 | 1.00 | MAPT (0.58) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL22803948 | 0.91 | HTR2B (0.59) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL5780884 | 0.84 | MAOB (0.51) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL22803507 | 0.81 | EPHX2 (0.58) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL30504235 | 0.80 | MAPT (0.62) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL28514997 | 0.80 | MAPT (0.62) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL12110170 | 0.79 | HTR2B (0.64) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL1148605 | 0.78 | HTR2B (0.62) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL28516762 | 0.77 | MAOB (0.74) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL5777726 | 0.77 | MAPT (0.46) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704714-B | Benzo five-membered and six-membered cyclic (thio) urea catalyst and application thereof in ring-opening polymerization | 浙江大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111704714-A | Benzo five-membered and six-membered ring (thio) urea catalyst and application thereof in ring-opening polymerization | 浙江大学 | 2020-09-25 | — | — | CN | disclosed |