SCHEMBL28516762

SCHEMBL28516762

Cn1ccc2cc(NC(=O)Nc3ccc(Cl)c(Cl)c3)ccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.74
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
MAPT P10636 5/20 0.62
HTR2B P41595 3/20 0.62
CYP1A2 P05177 3/20 0.62
CYP3A4 P08684 3/20 0.62
CYP2C19 P33261 3/20 0.62
TP53 P04637 2/20 0.62
CYP2D6 P10635 2/20 0.62
RECQL P46063 2/20 0.62
KDM4E B2RXH2 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
EPHX1 P07099 2/20 0.61
EPHX2 P34913 2/20 0.61
HTR2C P28335 4/20 0.60
NPC1 O15118 4/20 0.59
RAB9A P51151 3/20 0.59
LMNA P02545 2/20 0.59
CYP2C9 P11712 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8761254 0.87 MAOB (0.61) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL5779461 0.86 MAOB (0.82) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL15887043 0.85 MAOB (1.00) MAOBMEN1KMT2AMAPTKDM4E
SCHEMBL12110170 0.82 HTR2B (0.64) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL29757929 0.82 MAPT (0.55) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL26697218 0.82 MAPT (0.55) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL9400638 0.82 HTR2B (0.67) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL1148605 0.81 HTR2B (0.62) MAOBMEN1KMT2AMAPTHTR2B
Hydrochloric Acid SCHEMBL9400513 0.81 HTR2C (0.67) MAOBMEN1KMT2AMAPTHTR2B
SCHEMBL30504235 0.81 MAPT (0.62) MAOBMEN1KMT2AMAPTHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111704714-A Benzo five-membered and six-membered ring (thio) urea catalyst and application thereof in ring-opening polymerization 浙江大学 2020-09-25 CN disclosed