Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL2855672 | 1.00 | P2RX3 (0.39) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2853242 | 0.97 | P2RX3 (0.41) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2853447 | 0.97 | P2RX3 (0.41) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2853239 | 0.97 | P2RX3 (0.41) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| Formic Acid SCHEMBL2855641 | 0.93 | DYRK1A (0.43) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| Formic Acid SCHEMBL2858610 | 0.93 | DYRK1A (0.43) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL13528911 | 0.90 | DYRK1A (0.45) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2854214 | 0.90 | DYRK1A (0.45) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2853394 | 0.90 | DYRK1A (0.45) | P2RX3P2RX2CHRNA7HTR3AHTR3E | |
| SCHEMBL2853350 | 0.90 | DYRK1A (0.45) | P2RX3P2RX2CHRNA7HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828179-B1 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AGAINST CNS-RELATED DISEASES | MEMORY PHARM CORP (US) | 2010-01-20 | — | — | EP | claimed |