Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL25303606 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL25261836 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL28317821 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL25304483 | 0.98 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL28556296 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL4353876 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL23391403 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL28947094 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL23391391 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL28776254 | 0.96 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443134-A | Conjugates of cell binding molecules and camptothecin analogs | 杭州多禧生物科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114685414-A | Glycolipids for therapeutic use and pharmaceutical compositions thereof | 诺丁汉大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-106413753-B | Glycolipids for therapeutic use and pharmaceutical compositions thereof | 诺丁汉大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114040781-A | Formulation of conjugate of TUBULYSIN derivative and cell binding molecule | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-112272669-A | Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof | 杭州多禧生物科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-111278466-A | Liquid dosage forms of imatinib | 夫特弗制药私人有限公司 | 2020-06-12 | — | — | CN | disclosed |