Propiophenone

Propiophenone

SCHEMBL28517299

CCC(=O)c1ccccc1.CCCC(C)OC(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.49
MAPT P10636 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALDH1A1 P00352 4/20 0.43
RAB9A P51151 3/20 0.43
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 3/20 0.43
MEN1 O00255 2/20 0.43
PPARA Q07869 3/20 0.42
PRSS1 P07477 1/20 0.42
CTSG P08311 1/20 0.42
CTRB1 P17538 1/20 0.42
CMA1 P23946 1/20 0.42
LMNA P02545 2/20 0.40
CES1 P23141 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propiophenone SCHEMBL28509805 0.91 ALDH1A1 (0.50) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28517300 0.90 ALDH1A1 (0.56) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28517422 0.89 SMN1; SMN2 (0.47) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28509810 0.87 MAPT (0.51) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Acetophenone SCHEMBL28521681 0.86 ALDH1A1 (0.43) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28506667 0.86 SMN1; SMN2 (0.50) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28511629 0.83 SMN1; SMN2 (0.55) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
Propiophenone SCHEMBL28512012 0.81 SMN1; SMN2 (0.51) SMN1; SMN2MAPTL3MBTL1ALDH1A1RAB9A
SCHEMBL443825 0.80 ALDH1A1 (0.54) SMN1; SMN2ALDH1A1RAB9AHTTKMT2A
SCHEMBL349333 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111537-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109111539-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-109111538-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed