SCHEMBL28517375

SCHEMBL28517375

CCOC(=O)C(CC(C)C)C(C#N)(CC)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MMP8 P22894 1/20 0.36
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CYP2C9 P11712 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21313364 0.91 MMP8 (0.42) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL28520150 0.88 MEN1 (0.40) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL23142399 0.87 MEN1 (0.39) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL28519160 0.87 MEN1 (0.37) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL23142400 0.86 MEN1 (0.38) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL28511709 0.86 MEN1 (0.38) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL28312103 0.86 MEN1 (0.41) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL23142378 0.85 MEN1 (0.39) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL29072601 0.84 MEN1 (0.36) MEN1KMT2AMMP8ALDH1A1TSHR
SCHEMBL28510497 0.84 MEN1 (0.41) MEN1KMT2AMMP8CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107344979-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-107344978-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2020-06-09 CN claimed
CN-117924549-A Ziegler-Natta catalyst component, process for preparing the same, olefin polymerization catalyst and process for polymerizing olefin 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-116769078-A Catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-116769096-A Preparation method of high isotactic polybutene-1 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-116769091-A Preparation method of polybutene-1 resin 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-109111535-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-107344979-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109111538-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-107344978-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2020-06-09 CN disclosed