Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 3/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218042 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9217869 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9221413 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9220839 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285495 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9220711 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285088 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285382 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285493 | 1.00 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285266 | 0.99 | LMNA (0.75) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-0316704-B1 | Fluorocytidine derivatives, their preparation and medical preparations containing them | HOFFMANN LA ROCHE (CH) | 1995-07-12 | — | — | EP | claimed |
| EP-0316704-A2 | Fluorocytidine derivatives, their preparation and medical preparations containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-24 | — | — | EP | claimed |
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0316704-B1 | Fluorocytidine derivatives, their preparation and medical preparations containing them | HOFFMANN LA ROCHE (CH) | 1995-07-12 | — | — | EP | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| EP-0316704-A2 | Fluorocytidine derivatives, their preparation and medical preparations containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-24 | — | — | EP | disclosed |