Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167914 | 0.90 | KMT2A (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL164192 | 0.90 | KMT2A (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL562060 | 0.90 | KMT2A (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL11949518 | 0.90 | KMT2A (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL29670670 | 0.86 | DNMT1 (0.72) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL28511719 | 0.84 | DNMT1 (0.69) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL28511721 | 0.84 | DNMT1 (0.69) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL30463295 | 0.84 | DNMT1 (0.69) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL19244078 | 0.83 | DNMT1 (0.68) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL5306820 | 0.79 | KMT2A (0.80) | DNMT1KMT2ACYP2C19DNMT3BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390791-B | DNA methyltransferase 1 fluorescent probe and application thereof | 复旦大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-112390791-A | DNA methyltransferase 1 fluorescent probe and application thereof | 复旦大学 | 2021-02-23 | — | — | CN | disclosed |