Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | STAT3 | P40763 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949518 | 1.00 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL562060 | 1.00 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL30167914 | 1.00 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL28518031 | 0.90 | DNMT1 (0.81) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL5306820 | 0.89 | KMT2A (0.80) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL5306824 | 0.89 | KMT2A (0.80) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL19244077 | 0.87 | DNMT1 (0.76) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL30382095 | 0.87 | DNMT1 (0.76) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL21439464 | 0.87 | DNMT1 (0.76) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL14174620 | 0.87 | KMT2A (0.77) | KMT2ADNMT1CYP2C19DNMT3BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637498-B2 | PDLIM2 as a biomarker for cancer and as an anti-cancer treatment target | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2026-05-26 | — | — | US | claimed |
| CN-122070932-A | Application of combination of decitabine and anti-HER 2 antibody in preparation of medicines for treating tumors | 上海交通大学 | 2026-05-22 | — | — | CN | claimed |
| CN-116355836-B | Bile duct trunk cell expansion or passage system and application thereof | 上海市东方医院(同济大学附属东方医院) | 2026-05-19 | — | — | CN | claimed |
| EP-4729064-A1 | DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR TREATING OR PREVENTING DISC DEGENERATION | FibroBiologics, Inc. (US) | 2026-04-22 | — | — | EP | claimed |
| EP-3787647-B1 | DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR TREATING OR PREVENTING DISC DEGENERATION | FIBROBIOLOGICS INC (US) | 2026-04-15 | — | — | EP | claimed |
| EP-4719447-A2 | METHOD TO GENERATE INDUCED RETINAL PROGENITOR CELLS AND TREATMENT USING SUCH CELLS | Academia Sinica (TW) | 2026-04-08 | — | — | EP | claimed |
| US-20250311689-A1 | SEEDLING GERMINATION AND GROWTH CONDITIONS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2025-10-09 | — | — | US | claimed |
| US-12427128-B2 | Sensorineural hair cell differentiation | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2025-09-30 | — | — | US | claimed |
| CN-120118841-A | Composition, induction method and application of chemical reprogramming induction functional ciRPE cells | 瓯江实验室 | 2025-06-10 | — | — | CN | claimed |
| US-20250179578-A1 | METHOD FOR PREDICTING REACTIVITY TO ANTICANCER DRUGS BY ANALYZING GENOMIC DNA METHYLATION STATUS | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2025-06-05 | — | — | US | claimed |
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN, LTD. (CN) | 2016-05-26 | — | — | US | claimed |
| EP-3019596-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | Hong Guan Ltd. (CN) | 2016-05-18 | — | — | EP | claimed |
| US-20150259649-A1 | CELLULAR COMPOSITIONS USED TO RESTORE STEM CELL OR PROGENITOR CELL FUNCTION AND METHODS RELATED THERETO | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-09-17 | — | — | US | claimed |
| WO-2015003643-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN LTD. (CN) | 2015-01-15 | — | — | WO | claimed |
| US-20140255359-A1 | METHODS, KITS, AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL | STOWERS INSTITUTE FOR MEDICAL RESEARCH | 2014-09-11 | — | — | US | claimed |
| WO-2013059357-A1 | METHODS, KITS, AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL | STOWERS INSTITUTE FOR MEDICAL RESEARCH (US) | 2013-04-25 | — | — | WO | claimed |
| WO-2012038417-A1 | SUBSTITUTED AMINO - BENZOIC ACID DERIVATIVES AS INHIBITORS OF DNA METHYLTRANSFERASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2012-03-29 | — | — | WO | claimed |
| US-20100305059-A1 | COMPOSITION AND METHODS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-12-02 | — | — | US | claimed |
| WO-2008027049-A1 | COMPOSITION AND METHODS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-03-06 | — | — | WO | claimed |
| US-4283337-A | Process for the purification of tryptophane and derivatives of tryptophane | DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-08-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | AHCY, GSKIP, AHCYL1 | KMT2A 522/4885DNMT1 241/4885CYP2C19 4463/4885 |
| US-20100305059-A1 | COMPOSITION AND METHODS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA | DNMT3A, TET2, MCL1 | KMT2A 17/4885DNMT1 4/4885CYP2C19 1924/4885 |
| US-20150259649-A1 | CELLULAR COMPOSITIONS USED TO RESTORE STEM CELL OR PROGENITOR CELL FUNCTION AND METHODS RELATED THERETO | BMI1, DNMT1, DNMT3A | KMT2A 176/4885DNMT1 2/4885CYP2C19 4884/4885 |
| US-12637498-B2 | PDLIM2 as a biomarker for cancer and as an anti-cancer treatment target | HDAC2, HDAC1, HDAC11 | KMT2A 48/4885DNMT1 44/4885CYP2C19 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.