Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.30 |
| ▸ | GLRB | P48167 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295821 | 0.74 | — | — | |
| SCHEMBL8217234 | 0.69 | HCAR2 (0.44) | FAAHCES1 | |
| SCHEMBL9453492 | 0.69 | HCAR2 (0.44) | FAAHCES1 | |
| SCHEMBL24149771 | 0.69 | CA12 (0.43) | — | |
| SCHEMBL14738306 | 0.68 | — | — | |
| SCHEMBL3262436 | 0.67 | — | — | |
| SCHEMBL87629 | 0.66 | — | — | |
| SCHEMBL289070 | 0.66 | — | — | |
| SCHEMBL15870902 | 0.65 | — | — | |
| SCHEMBL7704419 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929337-A | OGA inhibitor compounds | 詹森药业有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114867725-A | OGA inhibitor compounds | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-112334461-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-112312908-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112313231-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112292377-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112292381-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |