Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 14/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738693 | 0.76 | TRPA1 (0.46) | TRPA1EPAS1MAP4K4MAPT | |
| SCHEMBL1144726 | 0.72 | MEN1 (0.44) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL29804933 | 0.72 | MEN1 (0.44) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL22685864 | 0.71 | BRD4 (0.43) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL29745481 | 0.71 | BRD4 (0.43) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL10456772 | 0.70 | TRPA1 (0.56) | TRPA1EPAS1MAP4K4ALDH1A1HSPB1 | |
| SCHEMBL15403615 | 0.69 | MAP4K4 (0.45) | TRPA1EPAS1MAP4K4HTTKMT2A | |
| SCHEMBL28509653 | 0.68 | EPAS1 (0.43) | TRPA1EPAS1MAP4K4ALDH1A1HSPB1 | |
| SCHEMBL30194212 | 0.68 | EPAS1 (0.43) | TRPA1EPAS1MAP4K4ALDH1A1HSPB1 | |
| SCHEMBL20160295 | 0.67 | EPAS1 (0.44) | TRPA1EPAS1ALDH1A1HPGDHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |