Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.58 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10255090 | 0.86 | GLA (0.64) | GLAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14899353 | 0.83 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2007035 | 0.83 | MEN1 (0.76) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL24715738 | 0.83 | MEN1 (0.62) | GLAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11372428 | 0.82 | ALDH1A1 (0.65) | GLAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL31512566 | 0.81 | ALDH1A1 (0.63) | GLAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4593391 | 0.81 | MAPT (0.73) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL4780753 | 0.80 | SMN1; SMN2 (0.72) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL13233264 | 0.80 | ALDH1A1 (0.67) | GLAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9191016 | 0.79 | ALDH1A1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341368-B | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-112341368-A | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2021-02-09 | — | — | CN | disclosed |