Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511602 | 0.77 | GRIN2B (0.53) | GRIN2B | |
| SCHEMBL18363718 | 0.66 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL18363724 | 0.66 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL11620512 | 0.63 | POLB (0.40) | — | |
| SCHEMBL29361094 | 0.60 | MAP4K4 (0.71) | — | |
| SCHEMBL15785404 | 0.60 | MAP4K4 (0.71) | — | |
| SCHEMBL2322786 | 0.60 | LDHA (0.54) | PARP1 | |
| SCHEMBL29377503 | 0.60 | KDM4E (0.65) | PARP1 | |
| SCHEMBL29378189 | 0.60 | PSMB5 (0.58) | GRIN2BPARP1 | |
| SCHEMBL4437681 | 0.60 | MAP4K4 (0.53) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-B | Substituted 4-azaindoles and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2021-02-09 | — | — | CN | claimed |