Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.77 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525921 | 0.87 | HDAC6 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29110747 | 0.84 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28524889 | 0.82 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28534046 | 0.76 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28850918 | 0.76 | HDAC6 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28177328 | 0.76 | HDAC6 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1595098 | 0.74 | HDAC6 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3631892 | 0.74 | GAA (0.57) | GAARAB9AMEN1KMT2APOLB | |
| SCHEMBL3630181 | 0.74 | GAA (0.57) | GAARAB9AMEN1KMT2APOLB | |
| SCHEMBL27768342 | 0.72 | CYP11B1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445896-B | Phenyl hydroxamic acid compound with anti-tumor activity and application thereof | 沈阳药科大学 | 2021-03-05 | — | — | CN | disclosed |