Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.67 |
| ▸ | TYR | P14679 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851960 | 1.00 | TRPV1 (0.67) | TRPV1TYRACHE | |
| SCHEMBL2855584 | 0.89 | TYR (0.58) | TRPV1TYRACHE | |
| SCHEMBL2855581 | 0.89 | TYR (0.58) | TRPV1TYRACHE | |
| SCHEMBL802713 | 0.89 | ABCB1 (0.65) | TRPV1TYRACHE | |
| SCHEMBL12299018 | 0.88 | TYR (0.73) | TRPV1TYRACHE | |
| SCHEMBL1916293 | 0.88 | TYR (0.73) | TRPV1TYRACHE | |
| SCHEMBL2847211 | 0.87 | TYR (0.61) | TRPV1TYRACHE | |
| SCHEMBL2847215 | 0.87 | TYR (0.61) | TRPV1TYRACHE | |
| SCHEMBL2853922 | 0.87 | MAPT (0.65) | TRPV1TYRACHE | |
| SCHEMBL2853919 | 0.87 | MAPT (0.65) | TRPV1TYRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778622-B1 | PARA-ALKYL-SUBSTITUTED N-(4-HYDROXY-3-METHOXY-BENZYL) CINNAMAMIDES AND THE USE THEREOF FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2010-01-13 | — | — | EP | claimed |