SCHEMBL1916293

SCHEMBL1916293

COc1cc(C=CC(=O)NCc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.73
ACHE P22303 1/20 0.71
TRPV1 Q8NER1 1/20 0.70
CYP2D6 P10635 2/20 0.67
CYP2C9 P11712 2/20 0.67
TSHR P16473 2/20 0.67
HSD17B10 Q99714 2/20 0.67
HDAC3 O15379 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
MMP9 P14780 2/20 0.67
CYP2C19 P33261 1/20 0.67
KDM4E B2RXH2 1/20 0.67
MEN1 O00255 1/20 0.67
PTGES O14684 1/20 0.67
CA12 O43570 1/20 0.67
DYRK3 O43781 1/20 0.67
PLIN1 O60240 1/20 0.67
KDM1A O60341 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12299018 1.00 TYR (0.73) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL7523925 0.95 TYR (0.71) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL7521409 0.95 TYR (0.79) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL7521416 0.95 TYR (0.79) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL7523933 0.95 TYR (0.71) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL12246735 0.93 TYR (0.63) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL14164369 0.93 TYR (0.70) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL802713 0.93 ABCB1 (0.65) TYRACHETRPV1HDAC3HDAC1
SCHEMBL9921185 0.92 MMP9 (0.71) TYRACHETRPV1CYP2D6CYP2C9
SCHEMBL2847211 0.91 TYR (0.61) TYRACHETRPV1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1774954-B1 Mouthwash and dentifrice and cleansing composition HENKEL AG & CO KGAA (DE) 2014-08-13 EP claimed
EP-2138152-A2 Sparkling-prickling mouthwash preparations Henkel AG & Co. KGaA (DE) 2009-12-30 EP claimed
WO-2008049651-A1 PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES HENKEL AG & CO. KGAA (DE) 2008-05-02 WO claimed
EP-1880705-A2 Brightening and/or colouring composition with improved product sensation HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP claimed
EP-1842573-A2 Brightening and/or colouring agent with improved product sensation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-10-10 EP claimed
WO-2007068403-A2 REMINERALIZING PRODUCTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-06-21 WO claimed
EP-1774955-A2 Ready-to-use mounthwash Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP claimed
EP-1774956-A2 Mouthwash and dentifrice and cleansing composition Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP claimed
EP-1774954-A2 Mouthwash and dentifrice and cleansing composition Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP claimed
EP-1774953-A2 Mouthwash concentrate Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP claimed
EP-2158894-B1 Oral cleansing agent HENKEL AG & CO KGAA (DE) 2018-11-07 EP disclosed
EP-2140853-B1 Coated particle for use in cosmetics HENKEL AG & CO KGAA (DE) 2018-07-18 EP disclosed
EP-2347754-B1 Oral and tooth care and cleaning agents with alkylpyridinium salts I HENKEL AG & CO KGAA (DE) 2018-01-24 EP disclosed
EP-2347753-B1 Oral and tooth care and cleaning agents with alkylpyridine salts II HENKEL AG & CO KGAA (DE) 2016-12-28 EP disclosed
EP-3003500-A1 ORAL AND DENTAL HYGIENE- AND CLEANING AGENTS FOR SENSITIVE TEETH Henkel AG & Co. KGaA (DE) 2016-04-13 EP disclosed
EP-1774953-A2 Mouthwash concentrate Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed
EP-1774954-A2 Mouthwash and dentifrice and cleansing composition Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-18 EP disclosed
EP-1323356-B1 Use of ferulic amides as flavouring agents SYMRISE GMBH & CO KG (DE) 2006-03-15 EP disclosed
US-20030152682-A1 Use of ferulic acid amides as flavor compounds SYMRISE AG (DE) 2003-08-14 US disclosed
EP-1323356-A2 Use of ferulic amides as flavouring agents HAARMANN & REIMER GMBH (DE) 2003-07-02 EP disclosed